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Description
Biotinylated LILRA3 His&Avi Tag Protein, HumanProduct Specification Species Human Synonyms LILRA3, ILT6, LIR4, CD85e Accession Q8N6C8 Amino Acid Sequence Gly24 Glu439, with C terminal 8*His&Avi tag
Product Specification
| Species | Human |
| Synonyms | LILRA3, ILT6, LIR4, CD85e |
| Accession | Q8N6C8 |
| Amino Acid Sequence | Gly24-Glu439, with C-terminal 8*His&Avi tag GPLPKPTLWAEPGSVITQGSPVTLRCQGSLETQEYHLYREKKTALWITRIPQELVKKGQFPILSITWEHAGRYCCIYGSHTAGLSESSDPLELVVTGAYSKPTLSALPSPVVTSGGNVTIQCDSQVAFDGFILCKEGEDEHPQCLNSHSHARGSSRAIFSVGPVSPSRRWSYRCYGYDSRAPYVWSLPSDLLGLLVPGVSKKPSLSVQPGPVVAPGEKLTFQCGSDAGYDRFVLYKEWGRDFLQRPGRQPQAGLSQANFTLGPVSRSYGGQYTCSGAYNLSSEWSAPSDPLDILITGQIRARPFLSVRPGPTVASGENVTLLCQSQGGMHTFLLTKEGAADSPLRLKSKRQSHKYQAEFPMSPVTSAHAGTYRCYGSLSSNPYLLTHPSDPLELVVSGAAETLSPPQNKSDSKAGEGGGSHHHHHHHHGLNDIFEAQKIEWHE |
| Expression System | HEK293 |
| Molecular Weight | 68-75kDa |
| Purity | >95% by SDS-PAGE |
| Endotoxin | <1EU/μg |
| Conjugation | Biotin |
| Tag | Avi Tag, His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, pH7.4 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference | 1、Knight J S. et al. (2017) Activated signature of antiphospholipid syndrome neutrophils reveals potential therapeutic target. JCI Insight. 2(18): e93897. |
Background
Leukocyte immunoglobulin-like receptor subfamily A member 3 (LILRA3) is also known as CD85 antigen-like family member E (CD85e), immunoglobulin-like transcript 6 (ILT-6) belongs to a family of leucocyte receptors. LILRA3 lacks a transmembrane domain and it is highly homologous to other LILR genes, and can bind human leukocyte antigen (HLA) class I. The biologic role of the LILRA3 molecule and the nature of its ligand are not known. LILRA3 can bind with high affinity to the surface of monocytes, leading to abolish LPS-induced TNF-alpha production by monocytes. It can be detected in B-cells, natural killer (NK) cells, peripheral blood monocytes and lung. LILRA3 transcripts are markedly upregulated in neutrophils from patients with antiphospholipid syndrome (APS). Some polymorphisms of the LILR genes are reported to be associated with susceptibility to diseases such as rheumatoid arthritis and multiple sclerosis.
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4.8 ★★★★★
Based on 1735 reviews
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Product Reviews
★★★★★ 5
Durable
My dog loves it. She takes it to bed every night. It is sturdy, doesn’t seem like it will rip easily.
Why did you pick this product vs others?:
Trying to replace a raccoon she got 4 year’s ago.
Squeak:
Only squeaks when I squeeze it.
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Reviewed in the United States on June 24, 2025
★★★★★ 5
As with all stuffed toys, supervision is needed.
I have a 6 month old standard size Golden Doodle who has gone through several raccoon toys. He loves their tails and to make them squeak. He knows the word raccoon, so when the last one “died”, I had to get another. This one is well made and has a magnificent tail. It did not take long, however, for Marvin to amputate two of the raccoon’s feet and pull the stuffing out. Luckily, I was able to get it from him before he swallowed any, and was able to sew up the injuries and return it to him for another round of play. I do not expect more from a stuffed toy, but I do not leave my dog alone with one and accept that supervision is always necessary. This raccoon is charming and when it “dies” I will probably buy it again. Five stars!
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Reviewed in the United States on August 26, 2020
★★★★★ 5
Worth the money
El destructo not able to tear this one apart although he gave it his best effort.
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Reviewed in the United States on May 8, 2026
★★★★★ 5
My Cardigan Corgi loves this toy!
My 33-lb. Cardigan Corgi loved her raccoon toy so much that she finally tore off its tail and I had to get her another one. Good toy for a medium-sized doggo.
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Reviewed in the United States on April 22, 2026
★★★★★ 1
Not worth the price.
No two weeks old and the top seam opened up
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Reviewed in the United States on May 31, 2026